Add to ORKGBackground: A pilot study was performed in order to investigate the effects of bariatric surgery on whole blood gene expression profiles in obese subjects with type 2 diabetes. Methodology/Principal Findings: Whole blood from eleven obese subjects with type 2 diabetes was collected in PAXgene tubes prior to and 6–12 months after bariatric surgery. Total RNA was isolated, amplified, labeled and hybridized to Illumina gene expression microarrays. Clinical and expression data were analyzed using a paired t-test, and correlations between changes in clinical trait and transcript levels were calculated. Pathways were identified using Ingenuity Pathway Analysis and DAVID gene ontology software. Overall, bariatric surgery resulted in significant re...
Background: Early metabolic responses following bariatric surgery appear greater than expected given...
Diabetes and Obesity are major diseases that affect Americans today. This project looks at insulin r...
The goal of this study was to provide insight into the mechanism by which bariatric surgical procedu...
A pilot study was performed in order to investigate the effects of bariatric surgery on whole blood ...
A pilot study was performed in order to investigate the effects of bariatric surgery on whole blood ...
Abstract Context Bariatric surgery has been shown to be effective in inducing complete remission of...
Obese patients who undergo gastric bypass surgery experience metabolic changes resulting in appetite...
Weight loss has been shown to significantly improve Adipose tissue (AT) function, however changes in...
We explored potential biomarkers and molecular mechanisms regarding multiple benefits after bariatri...
Abstract Background Obesity is reaching epidemic proportions and represents a significant risk facto...
To determine the impact of bariatric surgery and subsequent weight loss on clinical traits, a cohort...
BACKGROUND: Obesity, defined as pathologically increased body mass index (BMI), is strongly related ...
Biliopancreatic diversion with duodenal switch (BPD-DS) is a surgical intervention known to induce s...
The main roles of adipose tissue include triglycerides storage and adipokine secretion, which regula...
Supplementary Data for manuscript : Early changes in adipose tissue morphology, gene expression and ...
Background: Early metabolic responses following bariatric surgery appear greater than expected given...
Diabetes and Obesity are major diseases that affect Americans today. This project looks at insulin r...
The goal of this study was to provide insight into the mechanism by which bariatric surgical procedu...
A pilot study was performed in order to investigate the effects of bariatric surgery on whole blood ...
A pilot study was performed in order to investigate the effects of bariatric surgery on whole blood ...
Abstract Context Bariatric surgery has been shown to be effective in inducing complete remission of...
Obese patients who undergo gastric bypass surgery experience metabolic changes resulting in appetite...
Weight loss has been shown to significantly improve Adipose tissue (AT) function, however changes in...
We explored potential biomarkers and molecular mechanisms regarding multiple benefits after bariatri...
Abstract Background Obesity is reaching epidemic proportions and represents a significant risk facto...
To determine the impact of bariatric surgery and subsequent weight loss on clinical traits, a cohort...
BACKGROUND: Obesity, defined as pathologically increased body mass index (BMI), is strongly related ...
Biliopancreatic diversion with duodenal switch (BPD-DS) is a surgical intervention known to induce s...
The main roles of adipose tissue include triglycerides storage and adipokine secretion, which regula...
Supplementary Data for manuscript : Early changes in adipose tissue morphology, gene expression and ...
Background: Early metabolic responses following bariatric surgery appear greater than expected given...
Diabetes and Obesity are major diseases that affect Americans today. This project looks at insulin r...
The goal of this study was to provide insight into the mechanism by which bariatric surgical procedu...