Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morbid infections with limited therapeutic options. Previous studies have demonstrated that persistent intracellular infection of bladder epithelial cells (BEC) by UPEC contributes to recurrent UTI in mouse models of infection. However, the mechanisms employed by UPEC to survive within BEC are incompletely understood. In this study we aimed to understand the role of host vesicular trafficking proteins in the intracellular survival of UPEC. Using a cell culture model of intracellular UPEC infection, we found that the small GTPase Rab35 facilitates UPEC survival in UPEC-containing vacuoles (UCV) within BEC. Rab35 plays a role in endosomal recycling...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
Uropathogenic E. coli (UPEC) are the primary cause of urinary tract infections. Recent studies have ...
Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morb...
Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morb...
Uropathogenic Escherichia coli (UPEC) is the primary etiological agent of over 85% of community-acqu...
Uropathogenic Escherichia coli (UPEC), the principal cause of urinary tract infection in women, colo...
Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli, which are non-...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
Uropathogenic E. coli (UPEC) is the primary cause of urinary tract infections (UTI) affecting approx...
<p>Urinary tract infections (UTIs) are typically caused by bacteria that colonize different regions ...
Autophagy is a cellular recycling pathway, which in many cases, protects host cells from infections ...
Urinary tract infections (UTIs) are among the most common infections worldwide. Uropathogenic Escher...
Escherichia coli called as UPEC possessing specific urovirulence factors, helps in adhesion, surviva...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
Uropathogenic E. coli (UPEC) are the primary cause of urinary tract infections. Recent studies have ...
Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morb...
Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morb...
Uropathogenic Escherichia coli (UPEC) is the primary etiological agent of over 85% of community-acqu...
Uropathogenic Escherichia coli (UPEC), the principal cause of urinary tract infection in women, colo...
Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli, which are non-...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
Uropathogenic E. coli (UPEC) is the primary cause of urinary tract infections (UTI) affecting approx...
<p>Urinary tract infections (UTIs) are typically caused by bacteria that colonize different regions ...
Autophagy is a cellular recycling pathway, which in many cases, protects host cells from infections ...
Urinary tract infections (UTIs) are among the most common infections worldwide. Uropathogenic Escher...
Escherichia coli called as UPEC possessing specific urovirulence factors, helps in adhesion, surviva...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia col...
Uropathogenic E. coli (UPEC) are the primary cause of urinary tract infections. Recent studies have ...