Prostaglandin (PG) F2 Alpha Synthesis in Human Subcutaneous and Omental Adipose Tissue: Modulation by Inflammatory Cytokines and Role of the Human

Introduction: PGF2a may be involved in the regulation of adipose tissue function. Objectives: 1) To examine PGF2a release by primary preadipocytes, mature adipocytes and whole tissue explants from the subcutaneous and omental fat compartments; 2) To assess which PGF synthase is the most relevant in human adipose tissue. Methods: Fat samples were obtained by surgery in women. PGF2a release by preadipocytes, adipocytes and explants unde