Delay Of Insulin Addition To Oral Combination Therapy Despite Inadequate Glycemic Control Delay of Insulin Therapy

BACKGROUND: Patients and providers may be reluc-tant to escalate to insulin therapy despite inadequate glycemic control. OBJECTIVES: To determine the proportion of patients attaining and maintaining glycemic targets after initiat-ing sulfonylurea and metformin oral combination ther-apy (SU/MET); to assess insulin initiation among patients failing SU/MET; and to estimate the glycemic burden incurred, stratified by whether HbA1c goal was attained and maintained. DESIGN: Longitudinal observational cohort study