Coexistence of Ankylosing Spondylitis and Klinefelter’s Syndrome

Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Ankylosing spondylitis is a chronic inflammatory disease characterized by inflammatory lower back pain andmorning stiffness and accompanied by spine and sacroiliac joint involvement. Klinefelter’s syndrome is a genetic condition that only affectsmales. Affected males have an extra X chromosome.This paper reports a 30-years-oldmale on followupwith the diagnosis of Klinefelters syndrome. The patient admitted with complaints of inflammatory lower back, and neck pain and morning stiffness and was diagnosed with ankylosing spondylitis. Nonsteroidal anti-inflammatory drug and salazopyrine treatment resulted in significant regression in his complaints. 1