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Objectives: Debonding is a common occurrence in orthodontic treatment and a con-siderable number of orthodontists prefer to rebond the detached brackets because of economic issues. The aim of this study was to compare the microleakage beneath re-bonded stainless steel brackets using two methods of adhesive removal namely sandblast and laser. Materials and Methods: Sixty human premolar teeth were randomly divided into three groups. Following bonding the brackets, group 1 served as the control group. Brackets in groups 2 and 3 were debonded, and adhesive removal from the bracket bases was done by means of sandblasting and Er-YAG laser, respectively. After re-bonding, teeth in each group were stained with 2 % methylene blue for 24 hours, sec-tioned and examined under a stereomicroscope. Marginal microleakage at the adhe-sive-enamel and bracket-adhesive interfaces in the occlusal and gingival margins was determined. Statistical analysis was done using the Kruskal-Wallis test. Results: Comparison of the microleakage scores among the three groups revealed n