Add to ORKGThe currently available methods of assessing testicular toxicity and fertility are discussed. Compounds inducing testicular atrophy mainly affect the seminiferous epithelium, with progressive loss of sper-matozoa, spermatids, spermatocytes, and spermatogonia. Quantitative histometric analysis of sper-matogenesis, together with hormone assays, could be used to advantage in defining the underlying mechanisms of toxicity
yesThere is a need for improved reproductive toxicology assays that do not require large numbers of ...
Human sperm tests provide a direct means of assessing chemically induced spermatogenic dysfunction i...
Spermatogenesis involves the realization of a particular genetic program which requires a specific e...
Non-clinical safety assessment is essential during the drug development process in the pharmaceutica...
Reviews and studies on individual compounds were analyzed as to the suitability of different study d...
International audienceAlternative approaches for testicular toxicity Severe impairment of parameters...
International audienceTo measure the testicular toxicity of two fungicides (carbendazim and iprodion...
Recent declines in male fertility, as evidenced by decreased sperm counts, in industrialized nations...
To measure the testicular toxicity of two fungicides (carbendazim and iprodione), alone or in a mixt...
Thesis (Master's)--University of Washington, 2016-06In recent decades male reproductive health and f...
National audienceSeveral studies suggest that exposure to environmental pollutants is partly respons...
To address the pressing need for better in vitro testicular toxicity models, a workshop sponsored by...
Spermatogenesis involves the realization of a particular genetic program which requires a specific e...
International audienceA large variety of exogenous molecules such as therapeutic drugs, agriculture ...
International audienceMany toxicants are present in water as a mixture. Male infertility is one of t...
yesThere is a need for improved reproductive toxicology assays that do not require large numbers of ...
Human sperm tests provide a direct means of assessing chemically induced spermatogenic dysfunction i...
Spermatogenesis involves the realization of a particular genetic program which requires a specific e...
Non-clinical safety assessment is essential during the drug development process in the pharmaceutica...
Reviews and studies on individual compounds were analyzed as to the suitability of different study d...
International audienceAlternative approaches for testicular toxicity Severe impairment of parameters...
International audienceTo measure the testicular toxicity of two fungicides (carbendazim and iprodion...
Recent declines in male fertility, as evidenced by decreased sperm counts, in industrialized nations...
To measure the testicular toxicity of two fungicides (carbendazim and iprodione), alone or in a mixt...
Thesis (Master's)--University of Washington, 2016-06In recent decades male reproductive health and f...
National audienceSeveral studies suggest that exposure to environmental pollutants is partly respons...
To address the pressing need for better in vitro testicular toxicity models, a workshop sponsored by...
Spermatogenesis involves the realization of a particular genetic program which requires a specific e...
International audienceA large variety of exogenous molecules such as therapeutic drugs, agriculture ...
International audienceMany toxicants are present in water as a mixture. Male infertility is one of t...
yesThere is a need for improved reproductive toxicology assays that do not require large numbers of ...
Human sperm tests provide a direct means of assessing chemically induced spermatogenic dysfunction i...
Spermatogenesis involves the realization of a particular genetic program which requires a specific e...