RESEARCH Effects of ear ventricular pe function duri

Full list of author information is available at the end of the article significantly impaired after resuscitation (p <.05). The macro- and microcirculatory López et al. Intensive Care Medicine Experimental (2015) 3:14 DOI 10.1186/s40635-015-0049-ymicroscopy; Left ventricular functionchanges were associated with increased lactic acidosis and mixed venous O2 saturation when compared to baseline values (p <.05). The scatter plot between mean arterial pressure (MAP) and MFI showed a biphasic relationship, suggesting that the values were within the limits of microvascular autoregulation when MAP was above 71 ± 6 mm Hg (R2 = 0.63). Conclusions: Early hemodynamic resuscitation was effective to restore macrohemodynamia and myocardial contractility. Despite MAP and MFI were relatively preserved, the persistent microvascular dysfunction could explain metabolic disorders. The relationship between micro- and systemic hemodynamia and their impact on cellular function and metabolism needs to be further studied during endotoxic shock