Combining the pan-aurora kinase inhibitor AMG 900 with histone deacetylase inhibitors enhances antitumor activity in prostate cance
The Aurora Kinases are highly related serine-threonine kinases, essential for accurate and equal seg...
Aurora kinases are a family of protein kinases that have a key role in multiple stages of mitosis. O...
AbstractPatients with advanced stages of hepatocellular carcinoma (HCC) face a poor prognosis. Altho...
Histone deacetylase inhibitors (HDACIs) are being tested in clinical trials for the treatment of sol...
Aurora Kinase (AK) based therapy targeting AK-A & B is effective against some cancers. We have explo...
8 pagesInternational audienceAurora kinases are serine/threonine protein kinases that are involved i...
To determine whether MLN8054, an Aurora kinase A (Aurora-A) inhibitor causes radiosensitization in a...
Background Aurora kinase overexpression or amplifications are associated with high proliferation, po...
[[abstract]]Aurora kinase and FMS-like Tyrosine Receptor 3 (FLT3) was found to associate with variou...
Currently, sorafenib-based therapy is the standard treatment for advanced hepatocellular carcinoma (...
Motivated by the urgent need for new molecular targets and novel agents to treat pancreatic cancer, ...
Standard therapeutic approaches of cytotoxics and radiation in cancer are not only highly toxic, but...
Treating cancers has been one of the greatest challenges of biomedical research in the last few deca...
Histone deacetylase inhibitors (HDACIs) are showing promise as therapeutic agents for hematological ...
The Aurora proteins are a small family of serine/threonine kinase that function in various stages of...
The Aurora Kinases are highly related serine-threonine kinases, essential for accurate and equal seg...
Aurora kinases are a family of protein kinases that have a key role in multiple stages of mitosis. O...
AbstractPatients with advanced stages of hepatocellular carcinoma (HCC) face a poor prognosis. Altho...
Histone deacetylase inhibitors (HDACIs) are being tested in clinical trials for the treatment of sol...
Aurora Kinase (AK) based therapy targeting AK-A & B is effective against some cancers. We have explo...
8 pagesInternational audienceAurora kinases are serine/threonine protein kinases that are involved i...
To determine whether MLN8054, an Aurora kinase A (Aurora-A) inhibitor causes radiosensitization in a...
Background Aurora kinase overexpression or amplifications are associated with high proliferation, po...
[[abstract]]Aurora kinase and FMS-like Tyrosine Receptor 3 (FLT3) was found to associate with variou...
Currently, sorafenib-based therapy is the standard treatment for advanced hepatocellular carcinoma (...
Motivated by the urgent need for new molecular targets and novel agents to treat pancreatic cancer, ...
Standard therapeutic approaches of cytotoxics and radiation in cancer are not only highly toxic, but...
Treating cancers has been one of the greatest challenges of biomedical research in the last few deca...
Histone deacetylase inhibitors (HDACIs) are showing promise as therapeutic agents for hematological ...
The Aurora proteins are a small family of serine/threonine kinase that function in various stages of...
The Aurora Kinases are highly related serine-threonine kinases, essential for accurate and equal seg...
Aurora kinases are a family of protein kinases that have a key role in multiple stages of mitosis. O...
AbstractPatients with advanced stages of hepatocellular carcinoma (HCC) face a poor prognosis. Altho...
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