Research Article A Family History of Diabetes Modifies the Association between Elevated Urine Albumin Concentration and Hyperglycemia in Nondiabetic Mexican Adolescents

Copyright © 2015 Aida Jiménez-Corona et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We examined the frequency of elevated urine albumin concentration (UAC) and its association with metabolic syndrome (MetS) and metabolic markers in 515 nondiabetic Mexican adolescents stratified by family history of diabetes (FHD). UAC was measured in a first morning urine sample and considered elevated when excretion was ≥20mg/mL. MetS was defined using International Diabetes Federation criteria. Fasting insulin, insulin resistance, and lipids were evaluated. Multivariate logistic regression was performed. Elevated UACwas present in 12.4 % andMetS was present in 8.9 % of the adolescents. No association was found between elevated UAC and MetS. Among adolescents with FHD, 18.4 % were overweight and 20.7 % were obese, whereas, among those without a FHD, 15.9 % were overweight and 7.5 % were obese. Hyperglycemia was higher in those with elevated UAC than in thos