RESEARCH ARTICLE In vitro activity of tigecycl e h

Full list of author information is available at the end of the articleGlycylcyclines, are novel group of drugs which are tetracycline analogues that circumvent resistant mechanisms against tetracycline [1]. Tigecycline is the first member of the glycylcyclines group to be launched and acts on the ribosomes by inhibiting protein synthesis [2]. Tigecycline shows very good in vitro activity against Klebsiella pneumoniae and multi drug resistant (MDR) A. baumannii, it is also active against extended-spectrum beta-lactamase (ESBL) producing strains [1]. Tigecycline does not present cross-resistance with other antibiotics such as β lactams or fluoroquinolones [3]. A. baumannii has emerged as an important, troublesome nosocomial pathogen globally. Its clinical significance is due to its ability to easily acquire resistance determinants, mak-ing it one of the organisms threatening the currently avail