Primary Multiple Pulmon

Abstract: Primitive neuroectodermal tumors (PNETs) arising directly from the lung are extremely rare but particularly aggressive neoplasms. Although thoracic PNET usually develops on the chest wall, there have been reports of primary Ewing sarcoma/PNET of the lung. We present the case of a 16-year-old male with PNET diagnosed following histologic and immunohistochemical examination of a video-assisted thoracic surgical biopsy. As typically occurring for these tumors, the diagnosis was initially delayed in our patient and prognosis was poor despite aggressive surgical resection and postoperative che-motherapy. We attempted to explore the use of targeted pharmacother-apy through high-throughput sequencing in this case. We found that this treatment using Avastin and Cetuximab could provide a new therapeutic direction PNEN wall invol logical fea mind, and (Medicine Abbrev ohistoch P rimitEwin adolescen a slight m comprisi the comm humerus presence the chest is usually from the ment are pulmona adolescen 1 rtn on. ark nan loo ysi alp nti n, RA ed s s of t, es rap ose ty n ung e v re 1 anc erf