Add to ORKGInhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p1
T-cell Acute Lymphoblastic Leukemia (ALL) represents about 10-15 % of pediatric ALL cases. EZH2, one...
Background Many cancers show aberrant silencing of gene expression and overexpression of histone met...
Allogeneic hematopoietic cell transplantation is often complicated by graft versus host disease (GvH...
In acute myeloid leukemia (AML), therapy resistance frequently occurs, leading to high mortality amo...
PURPOSE: Chromosomal translocation of the mixed lineage leukemia (MLL) locus generates fusion protei...
Despite treatment with intensive chemotherapy, acute myelogenous leukemia (AML) remains an aggressiv...
Myelodysplastic syndrome (MDS) is characterized by clonal hematopoiesis and impaired differentiation...
Although global H3K27me3 reprogramming is a hallmark of cancer, no effective therapeutic strategy fo...
Despite treatment with intensive chemotherapy, acute myelogenous leukemia (AML) remains an aggressiv...
SummaryThe histone methyltransferase enhancer of Zeste homolog 2 (EZH2) is a candidate oncogene due ...
AbstractDNA methylation and histone methylation are both involved in epigenetic regulation of gene e...
The histone methyltransferase EZH2 plays a role in maintenance of the stem component of cancer, and ...
Background: EZH2 is a histone methyltransferase (HKMT) responsible for the maintenance of epigenetic...
Chemotherapy resistance is the main impediment in the treatment of acute myeloid leukaemia (AML). De...
EZH2, a histone methyltransferase, is overexpressed in several human tumors, but whether it exerts a...
T-cell Acute Lymphoblastic Leukemia (ALL) represents about 10-15 % of pediatric ALL cases. EZH2, one...
Background Many cancers show aberrant silencing of gene expression and overexpression of histone met...
Allogeneic hematopoietic cell transplantation is often complicated by graft versus host disease (GvH...
In acute myeloid leukemia (AML), therapy resistance frequently occurs, leading to high mortality amo...
PURPOSE: Chromosomal translocation of the mixed lineage leukemia (MLL) locus generates fusion protei...
Despite treatment with intensive chemotherapy, acute myelogenous leukemia (AML) remains an aggressiv...
Myelodysplastic syndrome (MDS) is characterized by clonal hematopoiesis and impaired differentiation...
Although global H3K27me3 reprogramming is a hallmark of cancer, no effective therapeutic strategy fo...
Despite treatment with intensive chemotherapy, acute myelogenous leukemia (AML) remains an aggressiv...
SummaryThe histone methyltransferase enhancer of Zeste homolog 2 (EZH2) is a candidate oncogene due ...
AbstractDNA methylation and histone methylation are both involved in epigenetic regulation of gene e...
The histone methyltransferase EZH2 plays a role in maintenance of the stem component of cancer, and ...
Background: EZH2 is a histone methyltransferase (HKMT) responsible for the maintenance of epigenetic...
Chemotherapy resistance is the main impediment in the treatment of acute myeloid leukaemia (AML). De...
EZH2, a histone methyltransferase, is overexpressed in several human tumors, but whether it exerts a...
T-cell Acute Lymphoblastic Leukemia (ALL) represents about 10-15 % of pediatric ALL cases. EZH2, one...
Background Many cancers show aberrant silencing of gene expression and overexpression of histone met...
Allogeneic hematopoietic cell transplantation is often complicated by graft versus host disease (GvH...