Add to ORKGAbstract. Leucine rich repeat kinase 2 (LRRK2) gene defects cause Parkinson’s disease (PD). Recently, LRRK2 has also been shown by genome wide association (GWA) studies to be a susceptibility gene for the disease. In India mutations in LRRK2 is a rare cause of PD.We, therefore, genotyped 64 SNPs across LRRK2 in 161 control samples and finally studied 6 haplotype tagging SNPs for association-based study on 300 cases and 446 ethnically matched controls to explore the potential role of LRRK2 as a susceptibility gene in PD for East Indians. We did not find any significant allele / genotype or haplotype associations with PD suggesting that common genetic variants within LRRK2 play limited role in modulating PD among East Indians. In addition, we...
disease: evidence for an R1628P founder Mutations in the leucine rich repeat kinase 2 (LRRK2) gene a...
Background: Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of P...
peer reviewedBackground: Genetic variability in LRRK2 has been unequivocally established as a major ...
Background: Genetic variability in LRRK2 has been unequivocally established as a major risk factor f...
Background: Genetic variability in LRRK2 has been unequivocally established as a major risk factor f...
Copyright © 2014 Aroma Agape Gopalai et al. This is an open access article distributed under the Cre...
Background : The frequency of leucine-rich repeat kinase 2 (LRRK2) G2019S mutation, the most common ...
Background : The frequency of leucine-rich repeat kinase 2 (LRRK2) G2019S mutation, the most common ...
Recent discovery of pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene in Parkins...
Recent discovery of pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene in Parkins...
The leucine-rich repeat kinase 2 (LRRK2) gene is of interest to Parkinson's disease (PD) as it has ...
Although the etiology of Parkinson’s disease (PD) remains unclear, there is increasing evidence of g...
Background Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Pa...
Background Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Pa...
Background Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Pa...
disease: evidence for an R1628P founder Mutations in the leucine rich repeat kinase 2 (LRRK2) gene a...
Background: Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of P...
peer reviewedBackground: Genetic variability in LRRK2 has been unequivocally established as a major ...
Background: Genetic variability in LRRK2 has been unequivocally established as a major risk factor f...
Background: Genetic variability in LRRK2 has been unequivocally established as a major risk factor f...
Copyright © 2014 Aroma Agape Gopalai et al. This is an open access article distributed under the Cre...
Background : The frequency of leucine-rich repeat kinase 2 (LRRK2) G2019S mutation, the most common ...
Background : The frequency of leucine-rich repeat kinase 2 (LRRK2) G2019S mutation, the most common ...
Recent discovery of pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene in Parkins...
Recent discovery of pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene in Parkins...
The leucine-rich repeat kinase 2 (LRRK2) gene is of interest to Parkinson's disease (PD) as it has ...
Although the etiology of Parkinson’s disease (PD) remains unclear, there is increasing evidence of g...
Background Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Pa...
Background Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Pa...
Background Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Pa...
disease: evidence for an R1628P founder Mutations in the leucine rich repeat kinase 2 (LRRK2) gene a...
Background: Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of P...
peer reviewedBackground: Genetic variability in LRRK2 has been unequivocally established as a major ...