. These authors contributed equally to this work. In recent years the use of natural dietary antioxidants to minimize the cytotoxicity and the damage induced in normal tissues by antitumor agents is gaining consideration. In literature, it is reported that vitamin C exhibits some degree of antineoplastic activity whereas Mitoxantrone (MTZ) is a synthetic anti-cancer drug with significant clinical effectiveness in the treatment of human malignancies but with severe side effects. Therefore, we have investigated the effect of vitamin C alone or combined with MTZ on MDA-MB231 and MCF7 human breast cancer cell lines to analyze their dose-effect on the tumor cellular growth, cellular death, cell cycle and cell signaling. Our results have evidence...
Breast cancer is the leading type of cancer in women. The majority of cells in the diagnosis of brea...
Doxorubicin is an anthracycline drug which inhibits the growth of breast cancer cell lines. However,...
Background/Aim: Recent studies provided convincing evidence for the anticancer activity of combined ...
<div><p>In recent years the use of natural dietary antioxidants to minimize the cytotoxicity and the...
Vitamin C may impact the efficiency of radiation therapy (RT) in breast cancer. The effects of RT al...
Vitamin C is generally thought to enhance immunity and is widely taken as a supplement especially du...
Vitamin C is generally thought to enhance immunity and is widely taken as a supplement especially du...
Background Biological and some clinical evidence suggest that high-dose intravenous vitamin C (IVC) ...
Background: Antioxidants may protect normal cells from the oxidative damage that occurs during radio...
Abstract: Despite the progress achieved in chemo- and radiotherapy, cancer is still a leading life-t...
High-dose of vitamin C (L-ascorbic acid, ascorbate) exhibits anti-tumoral effects, primarily mediate...
Copyright © 2015 Antonella Orlando et al. This is an open access article distributed under the Creat...
: These authors contributed equally to this work. Abstract: In previous papers, we presented data on...
While vitamin C has been proven to benefit the immune system during acute infections, there are now ...
D ow nloaded from 2 The mechanisms underlying the pathogenesis of estrogen-induced breast carcinogen...
Breast cancer is the leading type of cancer in women. The majority of cells in the diagnosis of brea...
Doxorubicin is an anthracycline drug which inhibits the growth of breast cancer cell lines. However,...
Background/Aim: Recent studies provided convincing evidence for the anticancer activity of combined ...
<div><p>In recent years the use of natural dietary antioxidants to minimize the cytotoxicity and the...
Vitamin C may impact the efficiency of radiation therapy (RT) in breast cancer. The effects of RT al...
Vitamin C is generally thought to enhance immunity and is widely taken as a supplement especially du...
Vitamin C is generally thought to enhance immunity and is widely taken as a supplement especially du...
Background Biological and some clinical evidence suggest that high-dose intravenous vitamin C (IVC) ...
Background: Antioxidants may protect normal cells from the oxidative damage that occurs during radio...
Abstract: Despite the progress achieved in chemo- and radiotherapy, cancer is still a leading life-t...
High-dose of vitamin C (L-ascorbic acid, ascorbate) exhibits anti-tumoral effects, primarily mediate...
Copyright © 2015 Antonella Orlando et al. This is an open access article distributed under the Creat...
: These authors contributed equally to this work. Abstract: In previous papers, we presented data on...
While vitamin C has been proven to benefit the immune system during acute infections, there are now ...
D ow nloaded from 2 The mechanisms underlying the pathogenesis of estrogen-induced breast carcinogen...
Breast cancer is the leading type of cancer in women. The majority of cells in the diagnosis of brea...
Doxorubicin is an anthracycline drug which inhibits the growth of breast cancer cell lines. However,...
Background/Aim: Recent studies provided convincing evidence for the anticancer activity of combined ...