ChIP-seq is increasingly being used for genome-wide profiling of histone modification marks. It is of particular importance to compare ChIP-seq data of two different conditions, such as disease vs. control, and identify regions that show differences in ChIP enrichment. We have developed a powerful and easy to use program, called diffReps, to detect those differential sites from ChIP-seq data, with or without biological replicates. In addition, we have developed two useful tools for ChIP-seq analysis in the diffReps package: one for the annotation of the differential sites and the other for finding chromatin modification ‘‘hotspots’’. diffReps is developed in PERL programming language and runs on all platforms as a command line script. We te...
BACKGROUND: ChIP-seq has become a routine method for interrogating the genome-wide distribution of v...
The genome-wide study of epigenetic states requires the integrative analysis of histone modification...
Mapping the chromosomal locations of transcription factors, nucleosomes, histone modifications, chro...
<div><p>ChIP-seq is increasingly being used for genome-wide profiling of histone modification marks....
<div><p>The advent of high-throughput technologies such as ChIP-seq has made possible the study of h...
Differentially changed genomic regions for histone marks were identified using the diffReps program,...
Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) is widely used to identi...
The advent of high-throughput technologies such as ChIP-seq has made possible the study of histone m...
Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) is widely used to identi...
Gene expression is the process of selectively reading genetic information and it describes a life-es...
Summary: Increasing number of ChIP-seq experiments are investigating transcription factor binding un...
Summary: Increasing number of ChIP-seq experiments are investigating transcription factor binding un...
Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-Seq) is a powerful t...
Mapping the chromosomal locations of transcription factors, nucleosomes, histone modifications, chro...
<div><p>Mapping the chromosomal locations of transcription factors, nucleosomes, histone modificatio...
BACKGROUND: ChIP-seq has become a routine method for interrogating the genome-wide distribution of v...
The genome-wide study of epigenetic states requires the integrative analysis of histone modification...
Mapping the chromosomal locations of transcription factors, nucleosomes, histone modifications, chro...
<div><p>ChIP-seq is increasingly being used for genome-wide profiling of histone modification marks....
<div><p>The advent of high-throughput technologies such as ChIP-seq has made possible the study of h...
Differentially changed genomic regions for histone marks were identified using the diffReps program,...
Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) is widely used to identi...
The advent of high-throughput technologies such as ChIP-seq has made possible the study of histone m...
Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) is widely used to identi...
Gene expression is the process of selectively reading genetic information and it describes a life-es...
Summary: Increasing number of ChIP-seq experiments are investigating transcription factor binding un...
Summary: Increasing number of ChIP-seq experiments are investigating transcription factor binding un...
Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-Seq) is a powerful t...
Mapping the chromosomal locations of transcription factors, nucleosomes, histone modifications, chro...
<div><p>Mapping the chromosomal locations of transcription factors, nucleosomes, histone modificatio...
BACKGROUND: ChIP-seq has become a routine method for interrogating the genome-wide distribution of v...
The genome-wide study of epigenetic states requires the integrative analysis of histone modification...
Mapping the chromosomal locations of transcription factors, nucleosomes, histone modifications, chro...