cause of hereditary recurrent fever. It is an auto- FMF patients to atherosclerosis [4,5]. Mean platelet vol- ITALIAN JOURNAL OF PEDIATRICS

Full list of author information is available at the end of the articleinflammatory disease, characterized by attacks of fever, abdominal pain, chest pain, arthritis, and skin rashes. Familial Mediterranean fever is common in people from Eastern Mediterranean region, especially in Sephardic Jewish, Armenian, Turkish, and Arabic population [1,2]. Systemic inflammation plays an important role in de-velopment and progression of atherosclerosis. The possi-bility of atherosclerosis was reported to be increased in cases with rheumatic diseases [1,3]. Case-control studies ume (MPV) and epicardial adipose tissue (EAT) thick-ness are novel parameters used in prediction of the risk of atherosclerosis [3,6-8]. Albeit contradictory results have been reported, there are some studies investigating the usefulness of MPV in assessment of atherosclerotic risk in cases with FMF [6,9,10]. However, no stud