A.: Automating Experimentation on

R factor = 0.045; wR factor = 0.094; data-to-parameter ratio = 8.1. In the title compound, C16H16BrNO4, the dihedral angle between the two aromatic rings is 67.51 (25). In the crystal, molecules are linked by N—H O hydrogen bonds involving the N—H and C O groups of the amide function, leading to a chain along [101]. Related literature For the synthesis and biological activity of 3,4,5-trimethoxy-benzamide derivatives, see: Buettner et al. (2009); Pellicani et al. (2012). For related structures, see: Saeed & Flörke (2009); Saeed et al. (2008); Choi et al. (2010)