Add to ORKGDYT1 dystonia is an inherited movement disorder caused by mutations inDYT1 (TOR1A), which codes for torsinA. Most of the patients have a trinucleotide deletion (ΔGAG) corre-sponding to a glutamic acid in the C-terminal region (torsinAΔE). Dyt1 ΔGAG heterozygous knock-in (KI) mice, which mimic ΔGAGmutation in the endogenous gene, exhibit motor defi-cits and deceased frequency of spontaneous excitatory post-synaptic currents (sEPSCs) and normal theta-burst-induced long-term potentiation (LTP) in the hippocampal CA1 region. Although Dyt1 KI mice show decreased hippocampal torsinA levels, it is not clear whether the decreased torsinA level itself affects the synaptic plasticity or torsinAΔE does it. To ana-lyze the effect of partial torsinA los...
A single GAG deletion in Exon 5 of the TOR1A gene is associated with a form of early-onset primary d...
A mutation in the coding region of the Tor1A gene, resulting in a deletion of a glutamic acid residu...
A mutation in the coding region of the Tor1A gene, resulting in a deletion of a glutamic acid residu...
104 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.A trinucleotide deletion of G...
104 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.A trinucleotide deletion of G...
Background DYT1 dystonia is a heritable, early-onset generalized movement disorder caused by a GAG d...
Dystonia represents the third most common movement disorder in humans with over 20 genetic loci iden...
<div><p>DYT1 dystonia is a debilitating neurological disease characterized by involuntary twisting m...
DYT1 dystonia is a debilitating neurological disease characterized by involuntary twisting movements...
A common form of the hyperkinetic movement disorder dystonia is caused by mutations in the gene TOR1...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
A single GAG deletion in Exon 5 of the TOR1A gene is associated with a form of early-onset primary d...
A single GAG deletion in Exon 5 of the TOR1A gene is associated with a form of early-onset primary d...
A mutation in the coding region of the Tor1A gene, resulting in a deletion of a glutamic acid residu...
A mutation in the coding region of the Tor1A gene, resulting in a deletion of a glutamic acid residu...
104 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.A trinucleotide deletion of G...
104 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.A trinucleotide deletion of G...
Background DYT1 dystonia is a heritable, early-onset generalized movement disorder caused by a GAG d...
Dystonia represents the third most common movement disorder in humans with over 20 genetic loci iden...
<div><p>DYT1 dystonia is a debilitating neurological disease characterized by involuntary twisting m...
DYT1 dystonia is a debilitating neurological disease characterized by involuntary twisting movements...
A common form of the hyperkinetic movement disorder dystonia is caused by mutations in the gene TOR1...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
DYT1 dystonia is a movement disorder caused by a deletion in the C-terminal of the protein torsinA. ...
A single GAG deletion in Exon 5 of the TOR1A gene is associated with a form of early-onset primary d...
A single GAG deletion in Exon 5 of the TOR1A gene is associated with a form of early-onset primary d...
A mutation in the coding region of the Tor1A gene, resulting in a deletion of a glutamic acid residu...
A mutation in the coding region of the Tor1A gene, resulting in a deletion of a glutamic acid residu...