RESEARCH ARTICLE re d Trial registration: Clinical Trials IRCT201008122496N4

Headache is one of the common complaints more fre-quent than common cold. It allocates almost 3 million vis-its to the Emergency Department (ED) in the United States. Most of patients presenting with headache have be-nign headaches that need symptomatic treatments [1]. Mi-graine typically starts in the 2nd decade of life, reaches its peak in the middle age, and its prevalence among women (18%) is more than among men (6%) [2,3]. The lifetime prevalence of migraine is at least 18 % [4]. In a study car-ried out on 405 patients with primary chronic headache, it was revealed that 95 % of the patients complained of ten-sion type headache and only 4 % of them suffered from chronic migraine headache [5]. The International Headache Society (IHS) has defined the migraine headache criteria related to the migraine headache as following