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Rotavirus infection is the leading cause of acute gastro-enteritis in infants and young children worldwide [1], and is estimated to cause over 146,000 hospital admissions per year in children aged <5 years in the World Health Organization (WHO) European region [2]. In the 23.6 million children aged <5 years in the European Union (EU) countries, 3.6 million episodes of rotavirus illness are estimated to occur annually, resulting in almost 700,000 outpatient visits, over 87,000 hospitalisations and 231 deaths per year [3]. Vaccination against rotavirus is recommended in guide-lines issued by the European Society for Paediatric Infec-tious Diseases and European Society for Paediatric Gastroenterology, Hepatology, and Nutrition [4,5], and b