Frontal sinus cholesterol granuloma: Case report

A case report of a massive cholesterol granuloma (CG) of the frontal sinus in a 15-year-old male subject treated endoscopically is reported. CGs are slowly expanding, cystic lesions that are rarely observed in the frontal sinus. Frontal sinus CGs characteristically present with proptosis, diplopia, and a unilateral painless expanding mass above the orbit. Patients frequently report a history of chronic nasal obstruction or head trauma. Although the pathogenesis is unclear, it is likely multifactorial in etiology. Surgical resection via endoscopic sinus surgery has been gaining popularity because of the minimally invasive approach and lower rates of recurrence. (Allergy Rhinol 5:e36–e38, 2014; doi: 10.2500/ar.2014.5.0073) Cholesterol granuloma (CG) is a histological entityconsisting of granulation tissue in which large numbers of cholesterol crystals within an enclosed space act as a powerful irritant and provoke foreign body giant cell formation.1 They are most commonly found in patients with chronic otitis media and cho-lesteatoma in the middle ear or mastoid portion of the temporal bone.2 CGs of the paranasal sinuses hav