Add to ORKGBackground: Volatile anesthetics are widely used in pediatric anesthesia but their potential neurotoxicity raise significant concerns regarding sequelae after anesthesia. However, whether physiological disturbance during anesthetic exposure contributes to such side effects remains unknown. The aim of the current study is to compare the neurotoxic effects of isoflurane and sevoflurane in 14 day old rat pups under spontaneous breathing or ventilated conditions. Methods: Postnatal 14 day rats were assigned to one of five groups: 1) spontaneous breathing (SB) + room air (control
Background and Objectives: Sevoflurane is a commonly used inhalational anaesthetic in clinics. Prolo...
ABSTRACT Background: We hypothesized that isoflurane has a greater potency to induce neurodegenerati...
Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical st...
BACKGROUND: Volatile anesthetics are widely used in pediatric anesthesia but their potential neuroto...
BACKGROUND:Numerous experiments in rodents suggest a causative link between exposure to general anae...
There is concern that clinical use of anesthetic drugs may cause neurotoxicity in the developing bra...
BackgroundMany anaesthetics when given to young animals cause cell death and learning deficits that ...
Numerous experiments in rodents suggest a causative link between exposure to general anaesthetics du...
Background Numerous experiments in rodents suggest a causative link between exposure to general anae...
Background Numerous experiments in rodents suggest a causative link between exposure to general anae...
Damage caused by administering general anesthetics to the developing brain in young children and pre...
Damage caused by administering general anesthetics to the developing brain in young children and pre...
Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical st...
Background: Structural brain abnormalities in newborn animals after prolonged exposure to all routin...
BACKGROUND: A wealth of data shows neuronal demise after general anesthesia in the very young rodent...
Background and Objectives: Sevoflurane is a commonly used inhalational anaesthetic in clinics. Prolo...
ABSTRACT Background: We hypothesized that isoflurane has a greater potency to induce neurodegenerati...
Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical st...
BACKGROUND: Volatile anesthetics are widely used in pediatric anesthesia but their potential neuroto...
BACKGROUND:Numerous experiments in rodents suggest a causative link between exposure to general anae...
There is concern that clinical use of anesthetic drugs may cause neurotoxicity in the developing bra...
BackgroundMany anaesthetics when given to young animals cause cell death and learning deficits that ...
Numerous experiments in rodents suggest a causative link between exposure to general anaesthetics du...
Background Numerous experiments in rodents suggest a causative link between exposure to general anae...
Background Numerous experiments in rodents suggest a causative link between exposure to general anae...
Damage caused by administering general anesthetics to the developing brain in young children and pre...
Damage caused by administering general anesthetics to the developing brain in young children and pre...
Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical st...
Background: Structural brain abnormalities in newborn animals after prolonged exposure to all routin...
BACKGROUND: A wealth of data shows neuronal demise after general anesthesia in the very young rodent...
Background and Objectives: Sevoflurane is a commonly used inhalational anaesthetic in clinics. Prolo...
ABSTRACT Background: We hypothesized that isoflurane has a greater potency to induce neurodegenerati...
Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical st...