Add to ORKGDOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progressio
The enzymes responsible for epigenetic modifications are key regulators of gene expression, ultimate...
Epigenetic control mechanisms are central to normal and malignant hematopoiesis. In this issue of Ca...
E-cadherin is a cell-cell adhesion protein fulfilling a prominent role in epithelial differentiation...
DOT1L has emerged as an anticancer target for MLL-associated leukaemias; however, its functional rol...
The histone lysine methyltransferase DOT1L (DOT1-like histone lysine methyltransferase) is responsib...
Abstract Background Epigenetics has been known to play a critical role in regulating the malignant p...
Breast cancer (BC) resistance to endocrine therapy results from constitutively active or aberrant es...
© 2017 American Association for Cancer Research. Myc oncoproteins exert tumorigenic effects by regu...
DOT1L is a unique histone methyltransferase that targets the histone H3 lysine 79 (H3K79) residue fo...
Eukaryotic gene regulation is a complex process requiring the action of many multicomponent complexe...
Although a large fraction of high-grade serous epithelial ovarian cancers (OCs) expresses Estrogen R...
Myc oncoproteins exert tumorigenic effects by regulating expression of target oncogenes. Histone H3 ...
<p>(A) Expression of CHD1L protein in MDA-MB-231 cells (MDA231), MDA-MB-231 cells transfected with c...
DOT1L is a methyltransferase which has been shown to methylate H3K79 (Ng et al. 2002; Feng et al. 20...
The enzymes responsible for epigenetic modifications are key regulators of gene expression, ultimate...
Epigenetic control mechanisms are central to normal and malignant hematopoiesis. In this issue of Ca...
E-cadherin is a cell-cell adhesion protein fulfilling a prominent role in epithelial differentiation...
DOT1L has emerged as an anticancer target for MLL-associated leukaemias; however, its functional rol...
The histone lysine methyltransferase DOT1L (DOT1-like histone lysine methyltransferase) is responsib...
Abstract Background Epigenetics has been known to play a critical role in regulating the malignant p...
Breast cancer (BC) resistance to endocrine therapy results from constitutively active or aberrant es...
© 2017 American Association for Cancer Research. Myc oncoproteins exert tumorigenic effects by regu...
DOT1L is a unique histone methyltransferase that targets the histone H3 lysine 79 (H3K79) residue fo...
Eukaryotic gene regulation is a complex process requiring the action of many multicomponent complexe...
Although a large fraction of high-grade serous epithelial ovarian cancers (OCs) expresses Estrogen R...
Myc oncoproteins exert tumorigenic effects by regulating expression of target oncogenes. Histone H3 ...
<p>(A) Expression of CHD1L protein in MDA-MB-231 cells (MDA231), MDA-MB-231 cells transfected with c...
DOT1L is a methyltransferase which has been shown to methylate H3K79 (Ng et al. 2002; Feng et al. 20...
The enzymes responsible for epigenetic modifications are key regulators of gene expression, ultimate...
Epigenetic control mechanisms are central to normal and malignant hematopoiesis. In this issue of Ca...
E-cadherin is a cell-cell adhesion protein fulfilling a prominent role in epithelial differentiation...