Research Article Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological

Copyright © 2015 Farahnaz Fatemi Naeini et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in anymedium, provided the originalwork is properly cited. Background. Mycosis fungoides (MF) is themost common subtype of cutaneous T-cell lymphoma. Extensive studies on IranianMF patients are absent. The present study aimed to produce updated clinical information on Iranian MF patients.Methods. This was a retrospective, descriptive, single-center study, including all cases ofMF seen in theDepartment ofDermatology, UniversityHospital of Isfahan, Iran, between 2003 and 2013. Data systematically recorded for each patient included clinical, biological, histological, and molecular findings. Results. Eighty-six patients with clinical and histologic diagnosis of MF were included in the study.Thirty-nine patients (45.3%) were male. Female predominance was observed in patients (male: female ratio is 1: 1.2). Patients were between 7 and 84 years of age (median: 41). The interval from disease onset to diagnosis ranged from 0 to 55 years (median: 1 year). Eighteen cases (20.9%) had unusual variants ofMF.Themost common types included hypopigmented and poikilodermatousMF. Childhood cases ofMF constituted 5.8 % (5/86) of all patients.The early stages were seen in 82 cases (95.34%).Conclusion.Themajor differences in epidemiologic characteristics of MF in Iran are the lack of male predominance and the lower age of patients at the time o