Research Article Intestinal Transportations of Main Chemical Compositions of Polygoni Multiflori Radix in Caco-2 Cell Model

permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Context. Polygoni Multiflori Radix (PMR) is originated from the root of Polygonum multiflorum Thunb. and used in oriental countries for centuries. However, little researches pay close attention to the absorption of its major constituents. Objective. Transepithelial transport of TSG, RL, PL, and four anthraquinones is carried out. Materials and Methods. Caco-2 cell monolayer, which represented a well-establishedmodel for the study of intestinal transport of nutrients and xenobiotics, was used in this paper. Results. The apparent permeability coefficients