Identity

Note—MIER1 was identified by differential display as an immediate-early gene activated during fibroblast growth factor (FGF) induction of mesoderm differentiation in Xenopus laevis. DNA/RNA A. Schematic illustrating the exon-intron organization of the human MIER1 gene Exons are shown as red bars/vertical lines and introns as horizontal lines; exon numbers are indicated below each schematic. The light red bar indicates the facultative intron 16 and the position of the alpha and beta carboxy-terminal coding regions are indicated. Note that the beta coding region is located within the facultative intron. The three alternate starts of translation, ML-, MF- and MAE- are indicated as are the three polyadenylation signals (PAS): i, ii and iii. B. Schematic illustrating the variant 5 ′ and 3 ′ ends of human MIER1 transcript