Clinical Study Resistance Exercise with Older Fallers: Its Impact on Intermuscular Adipose Tissue

Copyright © 2014 Janelle L. Jacobs et al.This is an open access article distributed under theCreative CommonsAttribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. Greater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was to determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention and if a greater reduction in IMAT occurs with eccentric versus traditional resistance training.Methods. Seventy-seven older adults (age 75.5 ± 6.8)withmultiple comorbidities and a history of falling completed a three-month exercise intervention pairedwith either eccentric or traditional resistance training.MRI of themid-thighwas examined at three time points to determine changes inmuscle composition after intervention. Results. No differences in IMAT were observed over time, and there were no differences in IMAT response between intervention groups. Participants in the traditional group lost a significant amount of lean tissue