ABSTRACT. Pregnant rats were treated with 30 mg/kg of methotrexate (MTX) on gestation day 13, and fetal brains were examined histo-pathologically from 6 to 48 hr after the treatment. In the telencephalon of the control group, there were few pyknotic neuroepithelial cells throughout the experimental period. Six hr after MTX treatment, several pyknotic neuroepithelial cells scattered throughout the telence-phalic wall. At 12–36 hr, pyknotic neuroepithelial cells increased significantly and were diffusely distributed throughout the telencephalic wall. Neuroepithelial cells were eliminated and showed sparse cell density at 36 hr in the telencephalon. Almost all fetuses died at 48 hr. Most of the pyknotic neuroepithelial cells were positively st...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
Methotrexate (MTX) is a folic acid antagonist, which is widely used as a cytotoxic chemotherapeutic ...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
ABSTRACT. Six-day-old rats were treated intraperitoneal injections with methotrexate 1 mg/kg, and th...
Methotrexate (MTX) is a cytostatic agent used in adjuvant chemotherapy for treatment of breast cance...
The purpose of this study was to determine if intrathecally administered methotrexate causes neurona...
Abstract. Methotrexate may cause seizures, dementia, and leukoencephalopathy when given in toxic dos...
Methotrexate (MTX) is a cytostatic agent widely used in combination with other agents as adjuvant ch...
Methotrexate is an anticancerous drug used most commonly in trophoblastic disease especially in ch...
This study evaluated the teratogenic potential of mathorexate on the central nervous system of CD-I ...
WOS: 000229276900016PubMed: 15866094Objective: To examine the effects of increasing doses of methotr...
Methotrexate (MTX) is a cytostatic agent used in adjuvant chemotherapy for treatment of breast cance...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
Methotrexate (MTX) is a cytostatic agent used in adjuvant chemotherapy for treatment of breast cance...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
Methotrexate (MTX) is a folic acid antagonist, which is widely used as a cytotoxic chemotherapeutic ...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
ABSTRACT. Six-day-old rats were treated intraperitoneal injections with methotrexate 1 mg/kg, and th...
Methotrexate (MTX) is a cytostatic agent used in adjuvant chemotherapy for treatment of breast cance...
The purpose of this study was to determine if intrathecally administered methotrexate causes neurona...
Abstract. Methotrexate may cause seizures, dementia, and leukoencephalopathy when given in toxic dos...
Methotrexate (MTX) is a cytostatic agent widely used in combination with other agents as adjuvant ch...
Methotrexate is an anticancerous drug used most commonly in trophoblastic disease especially in ch...
This study evaluated the teratogenic potential of mathorexate on the central nervous system of CD-I ...
WOS: 000229276900016PubMed: 15866094Objective: To examine the effects of increasing doses of methotr...
Methotrexate (MTX) is a cytostatic agent used in adjuvant chemotherapy for treatment of breast cance...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
Methotrexate (MTX) is a cytostatic agent used in adjuvant chemotherapy for treatment of breast cance...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...
Methotrexate (MTX) is a folic acid antagonist, which is widely used as a cytotoxic chemotherapeutic ...
Methotrexate is a cytostatic drug applied in adjuvant chemotherapy and associated with cognitive imp...