Frequency and Severity of the Dawn Phenomenon in Type 2 Diabetes Relationship to age

OBJECTIVEdTo know whether age has an independent effect on the dawn phenomenon in noninsulin-using type 2 diabetes. RESEARCH DESIGN AND METHODSdEighty-one individuals with type 2 diabetes were matched for HbA1c and divided by age into three subgroups of 27 individuals (1: $70 years; 2: 60–69 years; and 3: #59 years). All underwent ambulatory continuous glucose monitoring for quantifying the dawn phenomenon (i.e., the absolute [∂G, mg/dL] or relative [∂G%] increments from nocturnal nadirs to prebreakfast time points). RESULTSdHbA1c levels and 24-h glycemic profiles were similar across the three groups. Glucose increments (mean 6 SEM) were identical in the three groups: ∂G (mg/dL), 22.0