Add to ORKGAbstract One of the ultimate aims of imaging in biology is to achieve molecular localisation in the context of the structure of cells in their native state. Here, we review the current state of the art in cryo-soft X-ray tomography (cryo-SXT), which is the only imaging modality that can provide nanoscale 3D information from cryo-preserved, unstained, whole cells thicker than 1 μm. Correlative cryo-fluorescence and cryo-SXTadds functional information to structure, enabling studies of cellular events that cannot be captured using light, electron or X-ray microscopes alone
The diversity of living cells, in both size and internal complexity, calls for imaging methods with ...
AbstractCryo-soft X-ray tomography (cryo-SXT) is a powerful imaging technique that can extract ultra...
Developing in silico models that accurately reflect a whole, functional cell is an ongoing challenge...
3-D image of a cell. This meets a long-standing need in cell research and, as such, has enormous tra...
Imaging techniques are fundamental in order to understand cell organization and machinery in biologi...
In the context of cell biology, the term mesoscale describes length scales ranging from that of an i...
We can learn much about cell function by imaging and quantifying sub-cellular structures, especially...
Each class of microscope is limited to imaging specific aspects of cell structure and/or molecular o...
SiriusXT has developed a commercial bench top cryo soft X ray microscope (the SXT-100) for 3 D cryo ...
Fluorescence microscopy is a powerful tool for localising proteins within biological samp...
Cryo-soft X-ray tomography (cryo-SXT) is a powerful method to investigate the ultrastructure of cell...
Correlated imaging is the process of imaging a specimen with two complementary modalities, and then ...
AbstractSoft x-ray tomography (SXT) is increasingly being recognized as a valuable method for visual...
Background: Recent advances in nanoparticle design have generated new possibilities for nano-biotech...
Viruses are obligate intracellular pathogens that depend on their host cell machinery and metabolism...
The diversity of living cells, in both size and internal complexity, calls for imaging methods with ...
AbstractCryo-soft X-ray tomography (cryo-SXT) is a powerful imaging technique that can extract ultra...
Developing in silico models that accurately reflect a whole, functional cell is an ongoing challenge...
3-D image of a cell. This meets a long-standing need in cell research and, as such, has enormous tra...
Imaging techniques are fundamental in order to understand cell organization and machinery in biologi...
In the context of cell biology, the term mesoscale describes length scales ranging from that of an i...
We can learn much about cell function by imaging and quantifying sub-cellular structures, especially...
Each class of microscope is limited to imaging specific aspects of cell structure and/or molecular o...
SiriusXT has developed a commercial bench top cryo soft X ray microscope (the SXT-100) for 3 D cryo ...
Fluorescence microscopy is a powerful tool for localising proteins within biological samp...
Cryo-soft X-ray tomography (cryo-SXT) is a powerful method to investigate the ultrastructure of cell...
Correlated imaging is the process of imaging a specimen with two complementary modalities, and then ...
AbstractSoft x-ray tomography (SXT) is increasingly being recognized as a valuable method for visual...
Background: Recent advances in nanoparticle design have generated new possibilities for nano-biotech...
Viruses are obligate intracellular pathogens that depend on their host cell machinery and metabolism...
The diversity of living cells, in both size and internal complexity, calls for imaging methods with ...
AbstractCryo-soft X-ray tomography (cryo-SXT) is a powerful imaging technique that can extract ultra...
Developing in silico models that accurately reflect a whole, functional cell is an ongoing challenge...