PaPer TyPe www.landesbioscience.com Dermato-endocrinology e1-1

Necrobiosis lipoidica (NL) is a rare chronic granulomatous dermatitis first described in 1929 by Oppenheim that usually appears in the lower extremities that affects about 0.3–1.2 % of diabetic patients, the majority of whom have type 1 diabetes.