Deep sequencing technologies have the potential to transform the study of highly variable viral pathogens by providing a rapid and cost-effective approach to sensitively characterize rapidly evolving viral quasispecies. Here, we report on a high-throughput whole HIV-1 genome deep sequencing platform that combines 454 pyrosequencing with novel assembly and variant detection algorithms. In one subject we combined these genetic data with detailed immunological analyses t
Next-generation sequencing (NGS) technologies enable new insights into the diversity of virus popula...
With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (...
<div><p>Trade-offs between throughput, read length, and error rates in high-throughput sequencing li...
Deep sequencing technologies have the potential to transform the study of highly variable viral path...
<div><p>Deep sequencing technologies have the potential to transform the study of highly variable vi...
Deep sequencing is a powerful and cost-effective tool to characterize the genetic diversity and evol...
BACKGROUND: Pyrosequencing technology has the potential to rapidly sequence HIV-1 viral quasispecies...
Whole HIV-1 genome sequences are pivotal for large-scale studies of inter- and intrahost evolution, ...
Massively parallel sequencing (MPS) technologies, such as 454-pyrosequencing, allow for the identifi...
quasispecies and assessed the possible contribution of pyrosequencing technology in studying HIV-1 ...
[[abstract]]The first deep sequencing method was announced in 2005. Due to an increasing number of s...
Rapid evolution and high intrahost sequence diversity are hallmarks of human and simian immunodefici...
<div><p>Massively parallel sequencing (MPS) technologies, such as 454-pyrosequencing, allow for the ...
Many microbial populations rapidly adapt to changing environments with multiple variants competing f...
With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (...
Next-generation sequencing (NGS) technologies enable new insights into the diversity of virus popula...
With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (...
<div><p>Trade-offs between throughput, read length, and error rates in high-throughput sequencing li...
Deep sequencing technologies have the potential to transform the study of highly variable viral path...
<div><p>Deep sequencing technologies have the potential to transform the study of highly variable vi...
Deep sequencing is a powerful and cost-effective tool to characterize the genetic diversity and evol...
BACKGROUND: Pyrosequencing technology has the potential to rapidly sequence HIV-1 viral quasispecies...
Whole HIV-1 genome sequences are pivotal for large-scale studies of inter- and intrahost evolution, ...
Massively parallel sequencing (MPS) technologies, such as 454-pyrosequencing, allow for the identifi...
quasispecies and assessed the possible contribution of pyrosequencing technology in studying HIV-1 ...
[[abstract]]The first deep sequencing method was announced in 2005. Due to an increasing number of s...
Rapid evolution and high intrahost sequence diversity are hallmarks of human and simian immunodefici...
<div><p>Massively parallel sequencing (MPS) technologies, such as 454-pyrosequencing, allow for the ...
Many microbial populations rapidly adapt to changing environments with multiple variants competing f...
With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (...
Next-generation sequencing (NGS) technologies enable new insights into the diversity of virus popula...
With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (...
<div><p>Trade-offs between throughput, read length, and error rates in high-throughput sequencing li...