Background: Circulating lipids levels, as well as several familial lipid metabolism disorders, are strongly associated with initiation and progression of atherosclerosis and incidence of myocardial infarction (MI). Objectives: We hypothesized that genetic variants associated with circulating lipid levels would also be associated with MI incidence, and have tested this in three independent samples. Setting and Subjects: Using age- and sex-adjusted additive genetic models, we analyzed 554 single nucleotide polymorphisms (SNPs) in 41 candidate gene regions proposed to be involved in lipid-related pathways potentially predisposing to incidence of MI in 2,602 participants of the Swedish Twin Register (STR; 57 % women). All associations with nomi...
BackgroundGenome-wide association studies have identified multiple genomic loci associated with coro...
Abstract Background Genetic variation at 1p13 modulates serum lipid levels and the risk of coronary ...
Blood lipid levels are heritable, treatable risk factors for cardiovascular disease. We systematical...
Background: Circulating lipids levels, as well as several familial lipid metabolism disorders, are s...
Circulating lipids levels, as well as several familial lipid metabolism disorders, are strongly asso...
Background Circulating lipids levels, as well as several familial lipid metabolism disorders, are st...
Family history is a major risk factor for myocardial infarction (MI). However, known gene variants a...
Myocardial infarction (MI) is the major cardiovascular disease. This can be caused by mutual interac...
OBJECTIVE-: Genetic studies might provide new insights into the biological mechanisms underlying lip...
textabstractOBJECTIVE-: Genetic studies might provide new insights into the biological mechanisms un...
Acute myocardial infarction (AMI) is a pandemic in which conventional risk factors are inadequate to...
Myocardial infarction (MI) is a common complex disease with a genetic component. While several singl...
Background: Plasma lipid levels as well as coronary artery disease (CAD) have been shown to be highl...
Coronary artery disease and myocardial infarction (MI) are leading causes of death in the western wo...
OBJECTIVE: Circulating levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), hig...
BackgroundGenome-wide association studies have identified multiple genomic loci associated with coro...
Abstract Background Genetic variation at 1p13 modulates serum lipid levels and the risk of coronary ...
Blood lipid levels are heritable, treatable risk factors for cardiovascular disease. We systematical...
Background: Circulating lipids levels, as well as several familial lipid metabolism disorders, are s...
Circulating lipids levels, as well as several familial lipid metabolism disorders, are strongly asso...
Background Circulating lipids levels, as well as several familial lipid metabolism disorders, are st...
Family history is a major risk factor for myocardial infarction (MI). However, known gene variants a...
Myocardial infarction (MI) is the major cardiovascular disease. This can be caused by mutual interac...
OBJECTIVE-: Genetic studies might provide new insights into the biological mechanisms underlying lip...
textabstractOBJECTIVE-: Genetic studies might provide new insights into the biological mechanisms un...
Acute myocardial infarction (AMI) is a pandemic in which conventional risk factors are inadequate to...
Myocardial infarction (MI) is a common complex disease with a genetic component. While several singl...
Background: Plasma lipid levels as well as coronary artery disease (CAD) have been shown to be highl...
Coronary artery disease and myocardial infarction (MI) are leading causes of death in the western wo...
OBJECTIVE: Circulating levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), hig...
BackgroundGenome-wide association studies have identified multiple genomic loci associated with coro...
Abstract Background Genetic variation at 1p13 modulates serum lipid levels and the risk of coronary ...
Blood lipid levels are heritable, treatable risk factors for cardiovascular disease. We systematical...