Metastasis to the liver is a main factor in colorectal cancer mortality. Previous studies sug-gest that chronic psychological stress is important in cancer progression, but its effect on liver metastasis has not been investigated. To address this, we established a liver metasta-sis model in BALB/c nude mice to investigate the role of chronic stress in liver metastasis. Our data suggest that chronic stress elevates catecholamine levels and promotes liver metastasis. Chronic stress was also associated with increased tumor associated macro-phages infiltration into the primary tumor and increased the expression of metastatic genes. Interestingly, β-blocker treatment reversed the effects of chronic stress on liver metastasis. Our results suggest...
Chronic stress accelerates cancer growth in mice, according to a paper published in Nature Communica...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
Metastasis to the liver is a main factor in colorectal cancer mortality. Previous studies suggest th...
<p>β-adrenergic signaling significantly enhanced tumor cell dissemination to liver, and pharmacologi...
Psychological stress is an emotion experienced when people are under mental pressure or encounter un...
Psychological stress is an emotion experienced when people are under mental pressure or encounter un...
Psychological stress is an emotion experienced when people are under mental pressure or encounter un...
<div><p>Stress alters immunological and neuroendocrinological functions. An increasing number of stu...
Stress alters immunological and neuroendocrinological functions. An increasing number of studies ind...
Objectives: Chronic stress was previously reported to play a role in the development of oral cancer,...
Objectives: Chronic stress was previously reported to play a role in the development of oral cancer,...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
Chronic stress can promote tumor growth and progression through immunosuppressive effects and bi-dir...
Chronic stress can promote tumor growth and progression through immunosuppressive effects and bi-dir...
Chronic stress accelerates cancer growth in mice, according to a paper published in Nature Communica...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
Metastasis to the liver is a main factor in colorectal cancer mortality. Previous studies suggest th...
<p>β-adrenergic signaling significantly enhanced tumor cell dissemination to liver, and pharmacologi...
Psychological stress is an emotion experienced when people are under mental pressure or encounter un...
Psychological stress is an emotion experienced when people are under mental pressure or encounter un...
Psychological stress is an emotion experienced when people are under mental pressure or encounter un...
<div><p>Stress alters immunological and neuroendocrinological functions. An increasing number of stu...
Stress alters immunological and neuroendocrinological functions. An increasing number of studies ind...
Objectives: Chronic stress was previously reported to play a role in the development of oral cancer,...
Objectives: Chronic stress was previously reported to play a role in the development of oral cancer,...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
Chronic stress can promote tumor growth and progression through immunosuppressive effects and bi-dir...
Chronic stress can promote tumor growth and progression through immunosuppressive effects and bi-dir...
Chronic stress accelerates cancer growth in mice, according to a paper published in Nature Communica...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
To date stress, a highly complex process that disrupts homeostasis and involves environmental and ps...
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