Clinical Study Radiographic Parameters in Predicting Outcome of Patients with Hepatocellular Carcinoma Treated with

Copyright © 2013 Mohamed E. Salem et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. In patients with hepatocellular carcinoma, selection criteria for transarterial hepatic selective internal radiotherapy are imprecise. Additionally, radiographic parameters to predict outcome of transarterial hepatic selective internal radiotherapy have not been fully characterized. Patients and methods. Computed tomography (CT) scans of 23 patients with unresectable primary hepatocellular carcinoma before and after transarterial hepatic selective internal radiotherapy with yttrium-90 microspheres were retrospectively reviewed. Selected radiographic parameters were evaluated and correlatedwith progression-free survival and overall survival. Response to treatment was assessed with Response RECIST 1.1 andMorphology, Attenuation, Size, and Structure (MASS) criteria. Results. On the post-SIRT CT, 68 % of tumors demonstrated decreased size (median decrease of 0.8 cm