DNA pooling can provide an economic and efficient way to detect susceptibility loci to complex diseases. We carried out a genome screen with 400 microsatellite markers spaced at approximately 10 cm in two DNA pools consisting of 119 schizophrenia (SZ) patients and 119 controls recruited from a homogenous population in the Chang Le area of the Shandong peninsula of China. Association of D6S289, a dinucleotide repeat polymorphism in the JARID2 gene with SZ, was found and confirmed by individual genotyping (X2 = 17.89; P =.047). In order to refine the signal, we genotyped 14 single nucleotide polymorphisms (SNPs) covering JARID2 and the neighboring gene, DNTBP1, in an extended sample of 309 cases and 309 controls from Shandong peninsula (inclu...
Summary: Schizophrenia (SCZ) is a severe neuropsychiatric disorder that affects 1% of the global pop...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Context: Identifying susceptibility genes for schizophrenia may be complicated by phenotypic heterog...
DNA pooling can provide an economic and efficient way to detect susceptibility loci to complex disea...
DNA pooling can provide an economic and efficient way to detect susceptibility loci to complex disea...
Poster Board 734: abstract no. 2185Schizophrenia is a severe psychiatric disease with a lifetime ris...
BACKGROUND: Genome-wide association studies have detected a small number of weak but strongly suppor...
Objective: The authors sought to demonstrate that schizophrenia is a heterogeneous group of heritabl...
The cost of genome-wide association (GWA) studies can be prohibitively high when large samples are g...
To identify susceptibility loci for schizophrenia, we performed a two-stage genome-wide association ...
OBJECTIVE:\ud Some genome-wide scans and association studies for schizophrenia susceptibility genes ...
Background Schizophrenia (SCZ) is a very heterogeneous disease that affects approximately 1 % of the...
A full list of authors and affiliations appears at the end of the article. Summary Schizophrenia is ...
Schizophrenia is a complex idiopathic neuropsychiatric illness that affects approximately 1% of the...
The gene that codes for dopamine receptor D2 (DRD2 on chromosome 11q23) has long been a prime functi...
Summary: Schizophrenia (SCZ) is a severe neuropsychiatric disorder that affects 1% of the global pop...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Context: Identifying susceptibility genes for schizophrenia may be complicated by phenotypic heterog...
DNA pooling can provide an economic and efficient way to detect susceptibility loci to complex disea...
DNA pooling can provide an economic and efficient way to detect susceptibility loci to complex disea...
Poster Board 734: abstract no. 2185Schizophrenia is a severe psychiatric disease with a lifetime ris...
BACKGROUND: Genome-wide association studies have detected a small number of weak but strongly suppor...
Objective: The authors sought to demonstrate that schizophrenia is a heterogeneous group of heritabl...
The cost of genome-wide association (GWA) studies can be prohibitively high when large samples are g...
To identify susceptibility loci for schizophrenia, we performed a two-stage genome-wide association ...
OBJECTIVE:\ud Some genome-wide scans and association studies for schizophrenia susceptibility genes ...
Background Schizophrenia (SCZ) is a very heterogeneous disease that affects approximately 1 % of the...
A full list of authors and affiliations appears at the end of the article. Summary Schizophrenia is ...
Schizophrenia is a complex idiopathic neuropsychiatric illness that affects approximately 1% of the...
The gene that codes for dopamine receptor D2 (DRD2 on chromosome 11q23) has long been a prime functi...
Summary: Schizophrenia (SCZ) is a severe neuropsychiatric disorder that affects 1% of the global pop...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Context: Identifying susceptibility genes for schizophrenia may be complicated by phenotypic heterog...