Add to ORKGBackground: Parasite lactate dehydrogenase (pLDH) is extensively employed as malaria rapid diagnostic tests (RDTs). Moreover, it is a well-known drug target candidate. However, the genetic diversity of this gene might influence perfor-mance of RDT kits and its drug target candidacy. This study aimed to determine polymorphism of pLDH gene from Iranian isolates of P. vivax and P. falciparum. Methods: Genomic DNA was extracted from whole blood of microscopically confirmed P. vivax and P. falciparum infected patients. pLDH gene of P. falciparum and P. vivax was amplified using conventional PCR from 43 symptomatic malaria patients from Sistan and Baluchistan Province, Southeast Iran from 2012 to 2013. Results: Sequence analysis of 15 P. vivax LD...
BACKGROUND: Rapid diagnostic tests (RDTs) are becoming increasingly indispensable in malaria managem...
Abstract: This paper describes cloning of the gene coding for the lactate dehydrogenase (LDH) gene f...
Background: Plasmodium vivax is the most widespread species of Plasmodium in humans and causing abou...
Background: Parasite lactate dehydrogenase (pLDH) is extensively employed as malaria rapid diagnosti...
Background: The recently reported resistance to antimalarials contributes to making the control of m...
Background: The main goal of present study was to detect polymorphism in MSP-1 gene which is a major...
Background: Carboxy-terminal 42 kDa region of Plasmodium vivax merozoite surface protein-1 is consid...
Background: The aim of the study was to identify the prevalence of different species of Plasmodium a...
Abstract Background Antigen-detecting rapid diagnostic tests (RDTs) have been recommended by the Wor...
Background: Plasmodium vivax is the predominant species causes of malaria with about 90 % total annu...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human ma-laria, is resp...
Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Sub-region and now...
Background: Plasmodium vivax is responsible for approximately 80 million malaria cases in the world....
Purpose: Drug resistance is probably the greatest challenge to most malaria-control programmes. The ...
Background: Antimalarial drug resistance is one of the important challenges for governments in the f...
BACKGROUND: Rapid diagnostic tests (RDTs) are becoming increasingly indispensable in malaria managem...
Abstract: This paper describes cloning of the gene coding for the lactate dehydrogenase (LDH) gene f...
Background: Plasmodium vivax is the most widespread species of Plasmodium in humans and causing abou...
Background: Parasite lactate dehydrogenase (pLDH) is extensively employed as malaria rapid diagnosti...
Background: The recently reported resistance to antimalarials contributes to making the control of m...
Background: The main goal of present study was to detect polymorphism in MSP-1 gene which is a major...
Background: Carboxy-terminal 42 kDa region of Plasmodium vivax merozoite surface protein-1 is consid...
Background: The aim of the study was to identify the prevalence of different species of Plasmodium a...
Abstract Background Antigen-detecting rapid diagnostic tests (RDTs) have been recommended by the Wor...
Background: Plasmodium vivax is the predominant species causes of malaria with about 90 % total annu...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human ma-laria, is resp...
Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Sub-region and now...
Background: Plasmodium vivax is responsible for approximately 80 million malaria cases in the world....
Purpose: Drug resistance is probably the greatest challenge to most malaria-control programmes. The ...
Background: Antimalarial drug resistance is one of the important challenges for governments in the f...
BACKGROUND: Rapid diagnostic tests (RDTs) are becoming increasingly indispensable in malaria managem...
Abstract: This paper describes cloning of the gene coding for the lactate dehydrogenase (LDH) gene f...
Background: Plasmodium vivax is the most widespread species of Plasmodium in humans and causing abou...