Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus infection. Here we resolve the major genetic influences for NPC incidence using a genome-wide association study (GWAS), independent cohort replication, and high-resolution molecular HLA class I gene typing including 4,055 study participants from the Guangxi Zhuang Autonomous Region and Guangdong province of southern China. We detect and replicate strong association signals involving SNPs, HLA alleles, and amino acid (aa) variants across the major histocompatibility complex-HLA-A, HLA –B, and HLA-C class I genes (PHLA-A-aa-site-62 = 7.461
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Genetic susceptibility is one of the major etiological factors for nasopharyngeal carcinoma (NPC). A...
An association between specific human leukocyte antigens ( HLA) alleles and nasopharyngeal carcinoma...
<div><p>Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus...
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus infecti...
Abstract Background Nasopharyngeal carcinoma (NPC) is a multi-factorial malignancy closely associate...
Nasopharyngeal carcinoma (NPC) arises from the mucosal epithelium of the nasopharynx and is constant...
We have conducted a comprehensive case–control study of a nasopharyngeal carcinoma (NPC) population ...
curs at a disproportionately high rate among Chinese indi-viduals, is associated with Epstein-Barr v...
Background: Most HLA association studies with NPC focus on Southern part of China. Thus, little is k...
Background: Nasopharyngeal carcinoma (NPC), which occurs at a disproportionately high rate among Chi...
BACKGROUND: Most HLA association studies with NPC focus on Southern part of China. Thus, little is k...
Genetic factors, as well as environmental factors, play a role in development of nasopharyngeal carc...
Nasopharyngeal carcinoma (NPC) is an epithelial squamous cell carcinoma on the mucosal lining of th...
Background: The association between human leukocyte antigen (HLA) genes (located in the Major Histoc...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Genetic susceptibility is one of the major etiological factors for nasopharyngeal carcinoma (NPC). A...
An association between specific human leukocyte antigens ( HLA) alleles and nasopharyngeal carcinoma...
<div><p>Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus...
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus infecti...
Abstract Background Nasopharyngeal carcinoma (NPC) is a multi-factorial malignancy closely associate...
Nasopharyngeal carcinoma (NPC) arises from the mucosal epithelium of the nasopharynx and is constant...
We have conducted a comprehensive case–control study of a nasopharyngeal carcinoma (NPC) population ...
curs at a disproportionately high rate among Chinese indi-viduals, is associated with Epstein-Barr v...
Background: Most HLA association studies with NPC focus on Southern part of China. Thus, little is k...
Background: Nasopharyngeal carcinoma (NPC), which occurs at a disproportionately high rate among Chi...
BACKGROUND: Most HLA association studies with NPC focus on Southern part of China. Thus, little is k...
Genetic factors, as well as environmental factors, play a role in development of nasopharyngeal carc...
Nasopharyngeal carcinoma (NPC) is an epithelial squamous cell carcinoma on the mucosal lining of th...
Background: The association between human leukocyte antigen (HLA) genes (located in the Major Histoc...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Genetic susceptibility is one of the major etiological factors for nasopharyngeal carcinoma (NPC). A...
An association between specific human leukocyte antigens ( HLA) alleles and nasopharyngeal carcinoma...