Add to ORKGIdentification of driver mutations in lung adenocarcinoma has led to development of targeted agents that are already approved for clinical use or are in clinical trials. Therefore, the number of biomarkers that will be needed to assess is expected to rapidly increase. This calls for the implementation of methods probing the mutational status of multiple genes for inoperable cases, for which limited cytological or bioptic material is available. Cytology specimens from 38 lung adenocarcinomas were subjected to the simultaneous assessment of 504 mutational hotspots of 22 lung cancer-associated genes using 10 nanograms of DNA and Ion Torrent PGM next-generation sequencing. Thirty-six cases were successfull
Identification of targetable molecular changes is essential for selecting appropriate treatment in p...
Background Molecular profiling of advanced non-small cell lung cancers (NSCLC) is essential to ident...
Introduction: Cell-free DNA (cfDNA) analysis offers a non-invasive method to identify sensitising an...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
Adenocarcinoma (AdC) is the most common subtype of lung cancer, the leading tumor worldwide for inci...
BACKGROUND Molecular testing of lung adenocarcinomas (ADCs) is crucial for therapy stratification of...
Detection of somatic mutations in non-small cell lung cancers ( NSCLCs), especially adenocarcinomas,...
AbstractDetection of somatic mutations in non–small cell lung cancers (NSCLCs), especially adenocarc...
We present a new next-generation sequencing-based method to identify somatic mutations of lung cance...
BACKGROUND: Cancer is first and foremost a disease of the genome. Specific genetic signatures within...
IntroductionMolecular genetic analyses of lung adenocarcinoma have recently become standard of care ...
Approximately 30% of tumor biopsies from patients with advanced-stage lung adenocarcinomas yield ins...
Background: With the increase in need for further, serial, testing of lung cancer specimens, exhaust...
IF 5.008International audienceAdvances in Next Generation Sequencing (NGS) technologies have improve...
Identification of targetable molecular changes is essential for selecting appropriate treatment in p...
Background Molecular profiling of advanced non-small cell lung cancers (NSCLC) is essential to ident...
Introduction: Cell-free DNA (cfDNA) analysis offers a non-invasive method to identify sensitising an...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
Adenocarcinoma (AdC) is the most common subtype of lung cancer, the leading tumor worldwide for inci...
BACKGROUND Molecular testing of lung adenocarcinomas (ADCs) is crucial for therapy stratification of...
Detection of somatic mutations in non-small cell lung cancers ( NSCLCs), especially adenocarcinomas,...
AbstractDetection of somatic mutations in non–small cell lung cancers (NSCLCs), especially adenocarc...
We present a new next-generation sequencing-based method to identify somatic mutations of lung cance...
BACKGROUND: Cancer is first and foremost a disease of the genome. Specific genetic signatures within...
IntroductionMolecular genetic analyses of lung adenocarcinoma have recently become standard of care ...
Approximately 30% of tumor biopsies from patients with advanced-stage lung adenocarcinomas yield ins...
Background: With the increase in need for further, serial, testing of lung cancer specimens, exhaust...
IF 5.008International audienceAdvances in Next Generation Sequencing (NGS) technologies have improve...
Identification of targetable molecular changes is essential for selecting appropriate treatment in p...
Background Molecular profiling of advanced non-small cell lung cancers (NSCLC) is essential to ident...
Introduction: Cell-free DNA (cfDNA) analysis offers a non-invasive method to identify sensitising an...