Add to ORKGBackground: Despite of intense research in early cancer detection, there is a lack of biomarkers for the reliable detection of malignant tumors, including non-small cell lung cancer (NSCLC). DNA methylation changes are common and relatively stable in various types of cancers, and may be used as diagnostic or prognostic biomarkers. Methods: We performed DNA methylation profiling of samples from 48 patients with stage I NSCLC and 18 matching cancer-free lung samples using microarrays that cover the promoter regions of more than 14,500 genes. We correlated DNA methylation changes with gene expression levels and performed survival analysis
Background: Non-small cell lung carcinoma (NSCLC) is a complex malignancy that owing to its heteroge...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in DNA sequenc...
Background: Despite of intense research in early cancer detection, there is a lack of biomarkers for...
Despite of intense research in early cancer detection, there is a lack of biomarkers for the reliabl...
<div><h3>Background</h3><p>Despite of intense research in early cancer detection, there is a lack of...
Purpose Non-small-cell lung cancer (NSCLC) is a tumor in which only small improvements in clinical o...
UnrestrictedLung cancer is the leading cause of cancer-related death in the United States. It is est...
IntroductionDNA methylation is part of the epigenetic regulatory mechanism present in all normal cel...
UnrestrictedLung cancer is the number one cancer killer in the United States. This disease is divide...
Lung cancer is the most lethal malignancy worldwide and late diagnosis is a significant factor contr...
Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of g...
<div><p>The aim of this study was to clarify the significance of DNA methylation alterations at prec...
The aim of this study was to clarify the significance of DNA methylation alterations at precancerous...
AbstractEpigenetic changes, including DNA methylation, are a common finding in cancer. In lung cance...
Background: Non-small cell lung carcinoma (NSCLC) is a complex malignancy that owing to its heteroge...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in DNA sequenc...
Background: Despite of intense research in early cancer detection, there is a lack of biomarkers for...
Despite of intense research in early cancer detection, there is a lack of biomarkers for the reliabl...
<div><h3>Background</h3><p>Despite of intense research in early cancer detection, there is a lack of...
Purpose Non-small-cell lung cancer (NSCLC) is a tumor in which only small improvements in clinical o...
UnrestrictedLung cancer is the leading cause of cancer-related death in the United States. It is est...
IntroductionDNA methylation is part of the epigenetic regulatory mechanism present in all normal cel...
UnrestrictedLung cancer is the number one cancer killer in the United States. This disease is divide...
Lung cancer is the most lethal malignancy worldwide and late diagnosis is a significant factor contr...
Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of g...
<div><p>The aim of this study was to clarify the significance of DNA methylation alterations at prec...
The aim of this study was to clarify the significance of DNA methylation alterations at precancerous...
AbstractEpigenetic changes, including DNA methylation, are a common finding in cancer. In lung cance...
Background: Non-small cell lung carcinoma (NSCLC) is a complex malignancy that owing to its heteroge...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in DNA sequenc...