BACKGROUND: CD151 is a member of the tetraspanin family, which interacts with laminin-binding integrins and other tetraspanins. This protein is implicated in motility, invasion, and metastasis of cancer cells, but the prevalence of CD151 expression in subtypes of breast cancers and its influence on clinical outcome remains to be evaluated. METHODS AND RESULTS: The immunohistochemistry-based tissue microarray analysis showed that 127 (14.3%) cases overexpressed CD151 among 886 breast cancer patients. CD151 overexpression was found to be significantly associated with larger tumour size, higher nodal stage, advanced stage, absence of oestrogen receptor and progesterone receptor, and human epidermal growth factor receptor 2 overexpression. CD15...
The molecular mechanisms underlying prostate cancer metastasis remain poorly understood. The tetrasp...
background: The proposed involvement of CD151 in breast cancer (BCa) progression is based on finding...
The immune microenvironment in inflammatory breast cancer (IBC) is poorly characterised, and molecul...
The tetraspanin CD151 forms stoichiometric complexes with laminin-binding integrins (e.g., α3β1, α6β...
Background: Tetraspanins are transmembrane proteins that serve as scaffolds for multiprotein complex...
ErbB2 human breast cancer is a major clinical problem. Prior results have suggested that tetraspanin...
ErbB2+ human breast cancer is a major clinical problem. Prior results have suggested that tetraspani...
AbstractErbB2+ human breast cancer is a major clinical problem. Prior results have suggested that te...
The tetraspanin CD151 acts as a promoter of metastasis and invasion in several tumors. However, the ...
Tetraspanin CD151 has been implicated in metastasis through forming complexes with different molecul...
Invasion and migration of cancer cells are crucial for the formation of secondary lesions. These req...
As a family of integral membrane proteins, tetraspanins have been functionally linked to a wide spec...
CD151, a tetraspanin family protein involved in cell-cell and cell-extracellular matrix interaction,...
Epithelial ovarian cancer is the fifth-leading cause of cancer-related death for women in North Amer...
CD151, a transmembrane protein of the tetraspanin family, is implicated in the regulation of cell-su...
The molecular mechanisms underlying prostate cancer metastasis remain poorly understood. The tetrasp...
background: The proposed involvement of CD151 in breast cancer (BCa) progression is based on finding...
The immune microenvironment in inflammatory breast cancer (IBC) is poorly characterised, and molecul...
The tetraspanin CD151 forms stoichiometric complexes with laminin-binding integrins (e.g., α3β1, α6β...
Background: Tetraspanins are transmembrane proteins that serve as scaffolds for multiprotein complex...
ErbB2 human breast cancer is a major clinical problem. Prior results have suggested that tetraspanin...
ErbB2+ human breast cancer is a major clinical problem. Prior results have suggested that tetraspani...
AbstractErbB2+ human breast cancer is a major clinical problem. Prior results have suggested that te...
The tetraspanin CD151 acts as a promoter of metastasis and invasion in several tumors. However, the ...
Tetraspanin CD151 has been implicated in metastasis through forming complexes with different molecul...
Invasion and migration of cancer cells are crucial for the formation of secondary lesions. These req...
As a family of integral membrane proteins, tetraspanins have been functionally linked to a wide spec...
CD151, a tetraspanin family protein involved in cell-cell and cell-extracellular matrix interaction,...
Epithelial ovarian cancer is the fifth-leading cause of cancer-related death for women in North Amer...
CD151, a transmembrane protein of the tetraspanin family, is implicated in the regulation of cell-su...
The molecular mechanisms underlying prostate cancer metastasis remain poorly understood. The tetrasp...
background: The proposed involvement of CD151 in breast cancer (BCa) progression is based on finding...
The immune microenvironment in inflammatory breast cancer (IBC) is poorly characterised, and molecul...