Cinacalcet in Pediatric and Ado Kidney Disease

Abstract: Cinacalcet, a calcimimetic drug, has been shown to be efficacious in adult chronic kidney disease (CKD) patients; however, it was not fully studied in pediatric CKD patients. We aimed at assessing the effect of cinacalcet on intact parathyroid hormone (iPTH) secretion in children with CKD-4/5 with iPTH consistently 300 pg/mL refrac-tory to conventional treatment. This is a prospective cohort analysis of 28 children with uncon-trolled hyp to a tertia Twent regarding andmedic with CKD with CKD automated and 18 ye All pa Highly sig levels was (P), and C with no h almost in Cinaca patients w most of th (Medicine Abbrev blood u receptor filtration hormo