Experimental Crystal data

R factor = 0.037; wR factor = 0.102; data-to-parameter ratio = 14.5. The molecular and crystal structures of the title compound, C16H14FN3O2, are stabilized by intramolecular N—H O and intermolecular O—H O hydrogen bonds. The existence of non-classical intramolecular C—H N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and pyrimidinone rings of 7.9 (1). Related literature For the pharmacological activity of N3 and C7 disubstituted quinazolines, see: Usha et al. (2006). For the synthesis of quinazolinone and thienopyrimidinones, see: Yang et al. (2008). For synthesis, drug discovery and crystal structures