The proinflammatory cytokine interleukin (IL)-1b is im-plicated in the development of insulin resistance and b-cell dysfunction, whereas higher circulating levels of IL-1 receptor antagonist (IL-1RA), an endogenous inhib-itor of IL-1b, has been suggested to improve glycemia and b-cell function in patients with type 2 diabetes. To elucidate the protective role of IL-1RA, this study aimed to identify genetic determinants of circulating IL-1RA concentration and to investigate their associations with immunological and metabolic variables related to cardiometabolic risk. In the analysis of seven discovery and four replication cohort studies, two single nucleo-tide polymorphisms (SNPs) were independently associ-ated with circulating IL-1RA concen...
Objective: Proinflammatory cytokine IL-1 beta is capable of decreasing insulin-induced glucose trans...
To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1...
BACKGROUND: To investigate potential cardiovascular and other effects of long-term pharmacological i...
The proinflammatory cytokine interleukin (IL)-1b is im-plicated in the development of insulin resist...
The pro-inflammatory cytokine interleukin (IL)-1beta is implicated in the development of insulin res...
The pro-inflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin r...
The proinflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin resista...
The proinflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin resista...
The proinflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin resista...
The natural anti-inflammatory protein interleukin-1 receptor antagonist (IL-1Ra) inhibits the activi...
Background To investigate potential cardiovascular and other effects of long-term pharmacological in...
OBJECTIVE — Interleukin-1 receptor antagonist (IL-1Ra), a natural inhibitor of interleukin-1, has be...
Interleukin-1 (IL-1) plays an essential role in the immune pro-inflammatory process, which is regard...
AbstractInterleukin-1 receptor antagonist (IL-1ra) has been shown to play a crucial role in the prev...
To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1...
Objective: Proinflammatory cytokine IL-1 beta is capable of decreasing insulin-induced glucose trans...
To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1...
BACKGROUND: To investigate potential cardiovascular and other effects of long-term pharmacological i...
The proinflammatory cytokine interleukin (IL)-1b is im-plicated in the development of insulin resist...
The pro-inflammatory cytokine interleukin (IL)-1beta is implicated in the development of insulin res...
The pro-inflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin r...
The proinflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin resista...
The proinflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin resista...
The proinflammatory cytokine interleukin (IL)-1β is implicated in the development of insulin resista...
The natural anti-inflammatory protein interleukin-1 receptor antagonist (IL-1Ra) inhibits the activi...
Background To investigate potential cardiovascular and other effects of long-term pharmacological in...
OBJECTIVE — Interleukin-1 receptor antagonist (IL-1Ra), a natural inhibitor of interleukin-1, has be...
Interleukin-1 (IL-1) plays an essential role in the immune pro-inflammatory process, which is regard...
AbstractInterleukin-1 receptor antagonist (IL-1ra) has been shown to play a crucial role in the prev...
To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1...
Objective: Proinflammatory cytokine IL-1 beta is capable of decreasing insulin-induced glucose trans...
To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1...
BACKGROUND: To investigate potential cardiovascular and other effects of long-term pharmacological i...