Case Report Collagenous Colitis Associated with Protein Losing Enteropathy in a Toddler

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Collagenous mucosal inflammatory disease is a rare gastrointestinal disorder that involves the columnar lining of gastric and intestinal mucosa and is characterized by a distinct subepithelial collagen deposition. Recent clinical and pathological evidence have indicated that collagenous mucosal inflammatory disease can be extensive disease that may concomitantly involve several gastrointestinal sites at the same time. This entity, however, occurs infrequently in children. It is even less common to find concomitant depositions of collagen in the mucosa of gastrointestinal sites other than the colon. Only two cases in pediatric literature reported concomitant involvement, one with gastric and colonic involvement and the other one with gastroduodenocolitis. We are reporting a 15-month-old boy who presented with severe diarrhea and diffuse edema secondary to hypoalbuminemia. Further testing documented protein losing enteropathy (PLE) associated with collagenous colitis. 1. Case Report A 15-month-old male, with a past medical history significant for microcornea, was admitted to our hospital with progres-sive peripheral edema for two weeks. Parents reported 4-5 explosive diarrheal bowel movements per day for approxi