Add to ORKGCystic fibrosis (CF) is a major life-limiting genetic disease leading to severe respiratory symptoms caused by muta-tions in CF trans membrane conductance regulator (CFTR), a chloride channel expressed at the apical mem-brane of epithelial cells. Absence of functional CFTR from the surface of respiratory cells reduces mucociliary clear-ance, promoting airways obstruction, chronic infection and ultimately lung failure [1]. Despite major clinical advances treating the symptoms, which pushed survival beyond the second decade (~25 years in Europe), CF is still a life-limiting condition [2]. However, to further increase CF patients life expectancy, CF needs to be trea-ted beyond its symptoms, i.e., through treatments addres-sing the basic defect...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
ABSTRACT Cystic fibrosis (CF) remains the most common fatal hereditary lung disease. The discovery o...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
Cystic fibrosis (CF) is a severe hereditary and life-threatening disease in the Caucasian populatio...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis tr...
Cystic Fibrosis (CF) is the most common lethal genetic recessive disorder of Northern Europe, affect...
Cystic fibrosis (CF) is the most common life-limiting inherited condition in Caucasians. It is a mul...
Cystic fibrosis (CF) is caused by mutations in autosomal recessive genes that code for proteins cyst...
Rare diseases affect 400 million individuals worldwide and cause significant morbidity and mortality...
Cystic fibrosis (CF) is the most common and fatal autosomal recessive genetic disease in euro-descen...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
ABSTRACT Cystic fibrosis (CF) remains the most common fatal hereditary lung disease. The discovery o...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
Cystic fibrosis (CF) is a severe hereditary and life-threatening disease in the Caucasian populatio...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis tr...
Cystic Fibrosis (CF) is the most common lethal genetic recessive disorder of Northern Europe, affect...
Cystic fibrosis (CF) is the most common life-limiting inherited condition in Caucasians. It is a mul...
Cystic fibrosis (CF) is caused by mutations in autosomal recessive genes that code for proteins cyst...
Rare diseases affect 400 million individuals worldwide and cause significant morbidity and mortality...
Cystic fibrosis (CF) is the most common and fatal autosomal recessive genetic disease in euro-descen...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...
ABSTRACT Cystic fibrosis (CF) remains the most common fatal hereditary lung disease. The discovery o...
International audienceCystic fibrosis (CF) is an autosomal recessive disease caused by mutations in ...