Severe Leptospirosis with Multiple Organ Failure Successfully

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure. Case report. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed. The expected mortality was estimated at 90 % with clinical scores. The patient underwent plasma exchanges and high-volume hemofiltration (HVHF) with complete recovery of hepatic and kidney functions. Discussion. Plasma exchanges and HVHFmay confer survival benefit on patients with severe leptospirosis, refractory septic shock, andmultiple-organ failure. 1