Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential

# The Author(s) 2012. This article is published with open access at Springerlink.com Abstract Human stromal (mesenchymal) stem cells (hMSCs) are multipotent stem cells with ability to differentiate into mesoderm-type cells e.g. osteoblasts and adipocytes and thus they are being introduced into clinical trials for tissue regener-ation. Traditionally, hMSCs have been isolated from bone marrow, but the number of cells obtained is limited. Here, we compared the MSC-like cell populations, obtained from alter-native sources for MSC: adipose tissue and skin, with the standard phenotype of human bonemarrowMSC (BM-MSCs). MSC from human adipose tissue (human adipose stromal cells May Al-Nbaheen and Radhakrishnan vishnubalaji contributed equally to this paper. Electronic supplementary material The online version of this article (doi:10.1007/s12015-012-9365-8) contains supplementary material