RESEARCH ARTICLE Ultrasonographic Features of Hip Joints in Mucopolysaccharidoses Type I and II

Objectives The primary aim of this study was to assess the ultrasonographic features of hip joints in pa-tients with mucopolysaccharidosis (MPS) type I and II in comparison with healthy popula-tion. The secondary aims were to correlate these features with clinical measures and to evaluate the utility of ultrasound in the diagnosis of MPS disease. Materials and Methods SixteenMPS I (n = 3) and II (n = 13) patients were enrolled in the present study and underwent clinical and radiological evaluation, and bilateral high-resolution ultrasonography (US) of hip joints. The distance from the femoral neck to joint capsule (synovial joint space, SJS), joint effu-sion, synovial hyperthrophy, and local pathological vascularization were evaluated. The results were compared to the healthy population and correlated with clinical and radiological measures. Results 1. There was a difference in US SJS between children with MPS disease and the normative value for healthy population (7mm). Mean values of SJS were 15.81 ± 4.08 cm (right hi